[escepticos] ¿Infiltraciones de ozono para dolor de espalda?

[JM Mulet]

Muy interesante la referencia. Ahora empieza mi ignorancia: alguien sabe como se
ponen inyecciones de ozono? Utilizan algun precursor? o es agua oxigenada?
existe algún mecanismo que explique por que funciona?

saludos

JM


Missatge citat per Ramon Diaz-Alersi <ramon.diazalersi en gmail.com>:

> Perdón, este debí haberlo enviado en primer lugar:
>
> Spine (Phila Pa 1976). 2009 Jun 1;34(13):1337-44. Intramuscular oxygen-ozone
> therapy in the treatment of acute back pain with lumbar disc herniation: a
> multicenter, randomized, double-blind, clinical trial of active and
> simulated lumbar paravertebral injection. Paoloni M, Di Sante L, Cacchio A,
> Apuzzo D, Marotta S, Razzano M, Franzini M, Santilli V. Physical Medicine
> and Rehabilitation Unit, Azienda Policlinico Umberto I, Rome, Italy.
> paolonim en tin.it
> STUDY DESIGN: Multicenter randomized, double-blind, simulated
> therapy-controlled trial in a cohort of patients with acute low back pain
> (LBP) due to lumbar disc herniation (LDH).
> OBJECTIVE: To assess the benefit of intramuscular-paravertebral injections
> of an oxygen-ozone (O2O3) mixture.
> SUMMARY OF BACKGROUND DATA: Recent findings have shown that O2O3 therapy can
> be used to treat LDH that fails to respond to conservative management.
> However, these findings are based on intradiscal/intraforaminal O2O3
> injection, whereas intramuscular-paravertebral injection is the technique
> used most in clinical practice in Italy and other Western countries.
>  METHODS: Sixty patients suffering from acute LBP caused by LDH was
> randomized to an intramuscular O2O3 or control group. Patients were observed
> up to assess pain intensity, LBP-related disability, and drug intake (15
> [V2] and 30 [V3] days after treatment started, and 2 weeks [V4], and 3 [V5]
> and 6 [V6] months after treatment ended).
> RESULTS: A significant difference between the 2 groups in the percentage of
> cases who had become pain-free (61% vs. 33%, P < 0.05) was observed at V6.
> Patients who received O2O3 had a lower mean pain score than patients who
> received simulated therapy throughout the observation period. A significant
> improvement was observed in LBP-related disability in the study group
> patients when compared with the control group patients. Active O2O3 therapy
> was followed by a significantly lower number of days on nonsteroidal
> anti-inflammatory drugs at V2 and V3 and by a lower number of days at V4. No
> adverse events were reported.
> CONCLUSION: Treatment of LBP and sciatica is a major concern. Although the
> natural history of acute LBP is often self-limiting, conservative therapies
> are not always effective; in such cases, O2O3 intramuscular lumbar
> paravertebral injections, which are minimally invasive, seem to safely and
> effectively relieve pain, as well as reduce both disability and the intake
> of analgesic drugs.
>
> Saludos.
>
> ---
> Ramón Díaz-Alersi
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