Re: [escepticos] ¿Infiltraciones de ozono para dolor de espalda?

[Ramon Diaz-Alersi]

Spine (Phila Pa 1976). 2009 Jan 1;34(1):49-59. Injection therapy for
subacute and chronic low back pain: an updated Cochrane review. Staal JB, de
Bie RA, de Vet HC, Hildebrandt J, Nelemans P. Department of Epidemiology and
Caphri Research School, Maastricht University, P Debyeplein 1, Maastricht,
Netherlands. Bart.Staal en EPID.unimaas.nl
STUDY DESIGN: A systematic review of randomized controlled trials (RCTs).
OBJECTIVE: To determine if injection therapy is more effective than placebo
or other treatments for patients with subacute or chronic low back pain.
SUMMARY OF BACKGROUND DATA: The effectiveness of injection therapy for low
back pain is still debatable. Heterogeneity of target tissue,
pharmacological agent, and dosage, generally found in RCTs, point to the
need for clinically valid comparisons in a literature synthesis.
METHODS: We updated the search of the earlier systematic review and searched
the Cochrane Central Register of Controlled Trials, MEDLINE, and EMBASE
databases up to March 2007 for relevant trials reported in English, French,
German, Dutch, and Nordic languages. We also screened references from trials
identified. RCTs on the effects of injection therapy involving epidural,
facet, or local sites for subacute or chronic low back pain were included.
Studies that compared the effects of intradiscal injections, prolotherapy,
or ozone therapy with other treatments were excluded unless injection
therapy with another pharmaceutical agent (no placebo treatment) was part of
one of the treatment arms. Studies about injections in sacroiliac joints and
studies evaluating the effects of epidural steroids for radicular pain were
also excluded.
RESULTS: Eighteen trials (1179 participants) were included in this review.
The injection sites varied from epidural sites and facet joints (i.e.
intra-articular injections, peri-articular injections and nerve blocks) to
local sites (i.e. tender-and trigger points). The drugs that were studied
consisted of corticosteroids, local anesthetics, and a variety of other
drugs. The methodologic quality of the trials was limited with 10 of 18
trials rated as having a high methodologic quality. Statistical pooling was
not possible because of clinical heterogeneity in the trials. Overall, the
results indicated that there is no strong evidence for or against the use of
any type of injection therapy.
CONCLUSION: There is insufficient evidence to support the use of injection
therapy in subacute and chronic low-back pain. However, it cannot be ruled
out that specific subgroups of patients may respond to a specific type of
injection therapy.

Saludos.

---
Ramón Díaz-Alersi


El 4 de noviembre de 2009 21:44, Daurmith <daurmith en daurmith.com> escribió:

> Un compañero de trabajo con problemas de espalda me ha contado que está
> recibiendo inyecciones de ozono para el dolor. Me ha chocado mucho porque
> jamás había oído que el ozono pudiera servir para eso. He buscado un poco en
> quackwatch, pero sólo veo el uso de ozono para "curar" el cáncer, como
> siempre. ¿Alguien tiene más información, o puede indicarme dónde conseguir
> más? Google, obviamente, tiende a darme enlaces a sitios magufoides.
>
> Adela
>
> --
> La Biblioteca de Babel
> http://daurmith.blogalia.com
>
> _______________________________________________
> Escepticos mailing list
> Escepticos en dis.ulpgc.es
> http://correo.dis.ulpgc.es/mailman/listinfo/escepticos
>